The same here with 2.2.0 RC1. Tried with two different computers and I have exactly the same behavior. wsjtx.exe is running but no window or taskbar icon appear. Only visible in task manager. Also tried renaming the settings directory in order to have a "fresh" install first run, with no luck. Never used second monitor in order to have some confusion. When I revert to 2.1.2, everything works as usual.
The computers tested are: Desktop: Intel i3 4th gen. proc. with 8 GB ram OS Windows 10 64bit 1909 using the integrated Intel HD graphics 4400
Laptop: Intel i3 6th gen. proc. with 4 GB ram OS Windows 10 64bit 1909 using the integrated Intel HD graphics 520
At the desktop tried 32 bit and also 64 bit installers with no luck. At the laptop tried only 32 bit installer.