Currently using version 2.2.2 on Windows 10 with an IC-7300.
I have had this happen a few times now, but only when I double click to respond to a RX like the following....

WSJT-X just closes. I have to restart, change to the band I was on and restart the QSO. (it defaults back to the band and setting from when it was originally started).
Hard to pin this down because I don't see this kind of message too often. Last time it happened 3DA0RU was replying to me and caught me off guard.
I did manage to get through to him a little later so all is good!
Thanks for a great program!
73
Paul, AC9O