Thanks for the quick response. I had mentioned library error. Here are screen shots:. The sound card isn't the issue. That part works. The interface is a standard serial port using a multi-port card. If I set the rig to "none," I find the PTT works and it stops throwing errors (as you would expect). I also notice that if I try to use hardware handshake, the RTS setting is greyed out. I've tried every combination of handshake to no avail. These same settings work in MIXW4.