Unfortunately I encounter the same problems. On Windows 10, no screen or any other energy savings enabled. I keep my system turned or for spotting during the night and 24/24. Sometimes WSJT-X v2.2.2 stalls after just an hour, other moments it stops after 48 hours. The only thing I can find (as I added and debugged CAT to the uSDX firmware) is that there is an issue with the CAT communication. Some commands are repeated in a very high pace before the radio is able respond. These command are not only during ham's interaction with the radio, but also autonomous (e.g. checking frequency etc). Maybe this is something to check.